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Tottenham Hotspur will face Wolfsberger AC in the Europa League round of 32 on Wednesday night.
The north London club won the first leg 4-1 against the Austrian team, played in a neutral stadium in Budapest.
With such a healthy lead, Mourinho is likely to rotate his team for the second leg at Tottenham Hotspur Stadium today.
Before the game, the Portuguese coach has confirmed that Toby Alderweireld will play, who failed against West Ham. Eric Dier is struggling with form and confidence, and they could quit.
Spurs are going through a slump in form, having lost five times in their last six Premier League games. However, they have been impressive in the Europa League and will almost certainly advance to the next round.
On defense, Matt Doherty could come in on the wing, while Ben Davies will likely replace Sergio Reguilon on the left back. Japhet Tanganga should keep his place.
In the first leg, Harry Winks and Moussa Sissoko started with the Spurs and the pair will likely show up on Wednesday night as well.
Alli, 24, impressed in the first leg in Budapest, and the England midfielder should have another chance to impress. Gareth Bale is slowly rediscovering his form, and Mourinho has said the Welshman does not need to convince him.
Son Heung-Min should keep his place, but Carlos Vinicius could get off to an unusual start up front.
Tottenham’s expected starting line-up: Lloris, Doherty, Alderweireld, Tanganga, Davies; Winks, Sissoko; Son, Alli, Bale; Vinicius.