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Barcelona are scheduled to host Paris Saint-Germain in the first leg of the Champions League round of 16 on Tuesday night.
The Blaugrana will face Les Parisiens for the first time since the 2017 meeting in the same phase of the competition.
Back then, the Catalan giants suffered an embarrassing 4-0 away loss, but redeemed themselves with an impressive 6-1 win at Camp Nou to win 6-5 on aggregate.
In recent weeks there has been talk of the clash between Lionel Messi and Neymar, but it will not be the case if the latter is ruled out due to a calf injury.
The Paris Saint-Germain star will not face his former employers and is also a big doubt for the return leg at Parc des Princes.
However, Ronald Koeman’s team still has a test game on their hands and will have to play their best to secure an advantage in the first leg.
Philippe Coutinho (knee), Sergi Roberto (hamstring), Ansu Fati (meniscus), Ronald Araujo (ankle) are definitely discarded for the shock.
Gerard Piqué (match fitness) and Martin Braithwaite (adductor) can be part of the team based on the latest fitness tests.
Marc-Andre ter Stegen is practically an automatic pick in goal, but there may be changes in front of him.
Sergino Dest is likely to appear on the right back ahead of Oscar Mingueza after playing off the bench at the weekend following a minor muscle injury.
Frenkie de Jong has been the makeshift center-back alongside Clement Lenglet in recent games, but he can play higher up the field.
Koeman has previously described it as the full-back engine room and Samuel Umtiti could come in to accompany Lenglet into the heart of defense.
Gerard Piqué has returned to full training after a long-lasting knee injury, but he may not take a chance from the starting lineup against Les Parisiens.
Jordi Alba is an obvious choice for the left-back position when he’s in shape.
Sergio Busquets is ready to continue in the center position of the waiting field. De Jong should be ahead of the Spanish alongside Pedri, who has shown great maturity for his tender age.
Koeman should go with the best attack combination available to him. Antoine Griezmann and Ousmane Dembele are likely to appear on the flanks with Messi leading the way.
Messi has been in exceptional form with eight goals in his last five league games and it will be he who will have the responsibility to offer another outstanding display.
Barcelona’s expected lineup (4-3-3): Ter Stegen; Dest, Umtiti, Lenglet, Alba; Busquets, De Jong, Pedri; Dembélé, Messi, Griezmann.